Collaborations & Alliances

BioDuro, Pfizer Alliance Creates a Shelf-Stable Reagent

New Fluorosulfation reagent serves as a stable, solid alternative to toxic sulfuryl fluoride gas

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By: Kristin Brooks

Managing Editor, Contract Pharma

BioDuro LLC, a global life science R&D organization, has created AISF ([4-(Acetylamino)phenyl]-ImidodiSulfuryl diFluoride), a shelf-stable crystalline reagent for the synthesis of fluorosulfates and sulfamoyl fluorides. AISF was developed through a research collaboration with Pfizer.   Three attributes were sought for a solid reagent that could be an alternative to sulfuryl fluoride gas: the reagent must demonstrate comparable or improved reactivity to sulfuryl fluoride gas; it must be a c...

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